High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.

A monoclonal antibody for G protein-coupled receptor crystallography.

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists.

Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide.

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.

Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity.

Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes.

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins.