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If making selections (e.g., Subheadings, etc.), use the Send to Search Box feature to see PubMed records with those specifications. Select PubMed under the Links menu to retrieve all records for the MeSH Term. Select NLM MeSH Browser under the Links menu for additional information.

1: Clonidine Links

An alpha-2 adrenergic agonist that crosses the blood-brain barrier. Clonidine acts centrally by reducing sympathetic tone, resulting in a fall in diastolic and systolic blood pressure and a reduction in heart rate. It also acts peripherally, and this peripheral activity may be responsible for the transient increase in blood pressure seen during rapid intravenous administration. (From Martindale, the Extra Pharmacopoeia, 30th ed, p350)

Subheadings: This list includes those paired at least once with this heading in MEDLINE and may not reflect current rules for allowable combinations.

administration and dosageadverse effectsanalogs and derivativesanalysisantagonists and inhibitorsbloodcerebrospinal fluidchemical synthesischemistryclassificationcontraindicationsdiagnostic useeconomicshistoryimmunologyisolation and purificationmetabolismpharmacokineticspharmacologyphysiologypoisoningsupply and distributiontherapeutic usetoxicityurine

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Registry Number: 4205-90-7

Entry Terms:

Klofenil Clofenil M-5041T M 5041T M5041T ST-155 ST 155 ST155 Clonidine Monohydrobromide Monohydrobromide, Clonidine Clonidine Monohydrochloride Monohydrochloride, Clonidine Dixarit Clonidine Hydrochloride Hydrochloride, Clonidine Hemiton Isoglaucon Catapres Catapresan Catapressan Chlophazolin Clonidine Dihydrochloride Dihydrochloride, Clonidine Klofelin Clopheline Clofelin Gemiton

Previous Indexing:

Antihypertensive Agents (1966-1971) Imidazoles (1966-1971)

Pharmacologic Action:

Adrenergic alpha-Agonists Analgesics Antihypertensive Agents Sympatholytics

All MeSH Categories

Chemicals and Drugs Category

Heterocyclic Compounds

Heterocyclic Compounds, 1-Ring

Azoles

Imidazoles

Imidazolines

Clonidine

Year introduced: 1973(1972)

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