all[filt] - PubChem BioAssay Results (via Mowser)

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All: 1226

Confirmatory: 545 [image]

NIH MLP: 835 [image]

Primary Screening: 352 [image]

Protein Target: 605 [image]

Summary: 12

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Items 1 - 20 of 1226

1: AID: 1431Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Kallikrein 5 1536 HTS Dose Response Confirmation [Confirmatory]
Source: PCMD
Protein Target: RecName: Full=Coagulation factor XII; AltName: Full=Hageman factor; Short=HAF; Contains: RecName: Full=Coagulation factor XIIa heavy chain; Contains: RecName: Full=Beta-factor XIIa part 1; Contains: RecName: Full=Beta-factor XIIa part 2; Contains: RecName: Full=Coagulation factor XIIa light chain; Flags: Precursor [gi: 119763]
Compounds Active: 109;Â Tested: 1260
Description: Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...Â more

2: AID: 873Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Kallikrein 5 1536 HTS [Primary Screening]
Source: PCMD
Protein Target: kallikrein-related peptidase 5 preproprotein [Homo sapiens] [gi: 6912644]
Compounds Active: 1264;Â Tested: 214202
Description: Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...Â more

3: AID: 846Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Factor XIa 1536 HTS Dose Response Confirmation [Confirmatory]
Source: PCMD
Protein Target: coagulation factor XI [gi: 180352]
Compounds Active: 91;Â Tested: 302
Description: Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...Â more

4: AID: 1018Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Chemical Antagonists IAP-family anti-apoptotic proteins [Primary Screening]
Source: San Diego Center for Chemical Genomics
Protein Target: nuclear receptor subfamily 4, group A, member 1 [Homo sapiens] [gi: 27894344]
Compounds Active: 226;Â Tested: 195576
Description: Data Source: San Diego Center for Chemical Genomics (SDCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, San Diego, CA) Network:...Â more

5: AID: 1222Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature

High Throughput Screen for Inhibitors of ER Stress-induced Cell Death in a 384 well format. [Primary Screening]
Source: San Diego Center for Chemical Genomics
Compounds Active: 19;Â Tested: 187218
Description: Data Source: San Diego Center for Chemical Genomics (SDCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: ...Â more

6: AID: 1430Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

HTS assay for inhibitors of Trypanosoma brucei hexokinase 1 [Primary Screening]
Source: University of Pittsburgh Molecular Library Screening Center
Protein Target: hexokinase [Trypanosoma brucei] [gi: 70832125]
Compounds Active: 239;Â Tested: 220233
Description: Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African sle...Â more

7: AID: 1429Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Confirmation cell-based assay to identify antagonists of the Sphingosine 1-Phosphate Receptor 3 (S1P3) [Primary Screening]
Source: The Scripps Research Institute Molecular Screening Center
Protein Target: sphingosine-1-phosphate receptor 3 [Homo sapiens] [gi: 38788193]
Compounds Active: 63;Â Tested: 237
Description: Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...Â more

8: AID: 1428Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Antagonists at human 5-Hydroxytryptamine 5-HT1A receptor
Source: IUPHAR-DB
Protein Target: 5-hydroxytryptamine (serotonin) receptor 1A [Homo sapiens] [gi: 55956923]
Compounds Active: 34;Â Tested: 34
Description: This assay details affinity data for antagonists at human 5-Hydroxytryptamine 5-HT1A receptor, as described in the published literature. Where possib...Â more

9: AID: 1427Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Antagonists at rat 5-Hydroxytryptamine 5-HT1A receptor
Source: IUPHAR-DB
Protein Target: 5-hydroxytryptamine (serotonin) receptor 1A [Rattus norvegicus] [gi: 6981054]
Compounds Active: 2;Â Tested: 2
Description: This assay details affinity data for antagonists at rat 5-Hydroxytryptamine 5-HT1A receptor, as described in the published literature. Where possible...Â more

10: AID: 1426Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Allosteric regulators at human 5-Hydroxytryptamine 5-HT1A receptor
Source: IUPHAR-DB
Protein Target: 5-hydroxytryptamine (serotonin) receptor 1A [Homo sapiens] [gi: 55956923]
Substances Active: 1; Tested: 1
Description: This assay details affinity data for allosteric regulators at human 5-Hydroxytryptamine 5-HT1A receptor, as described in the published literature. Wh...Â more

11: AID: 1425Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Agonists at human 5-Hydroxytryptamine 5-HT1A receptor
Source: IUPHAR-DB
Protein Target: 5-hydroxytryptamine (serotonin) receptor 1A [Homo sapiens] [gi: 55956923]
Compounds Active: 54;Â Tested: 54
Description: This assay details affinity data for agonists at human 5-Hydroxytryptamine 5-HT1A receptor, as described in the published literature. Where possible ...Â more

12: AID: 1424Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Primary cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel N1 (TRPN1) [Primary Screening]
Source: The Scripps Research Institute Molecular Screening Center
Protein Target: transient receptor potential cation channel, subfamily N, member 1 [Danio rerio] [gi: 34330186]
Compounds Active: 390;Â Tested: 217969
Description: Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...Â more

13: AID: 1215Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Thrombin 1536 HTS Dose Response Confirmation [Confirmatory]
Source: PCMD
Protein Target: prothrombin [Homo sapiens] [gi: 339641]
Compounds Active: 223;Â Tested: 529
Description: Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...Â more

14: AID: 1423Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. [Primary Screening]
Source: NMMLSC
Protein Target: RGS8 protein [Homo sapiens] [gi: 74355113]
Compounds Active: 750;Â Tested: 218538
Description: University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...Â more

15: AID: 1422Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Inhibitors of the EP2 Prostaglandin E2 Receptor - Primary Screen [Primary Screening]
Source: Emory University Molecular Libraries Screening Center
Protein Target: prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo sapiens] [gi: 31881630]
Compounds Active: 1304;Â Tested: 250243
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Raymond Dingledine, Em...Â more

16: AID: 1421Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Modulators of the EP2 prostaglandin EP2 receptor - Primary Dose Response [Confirmatory]
Source: Emory University Molecular Libraries Screening Center
Protein Target: prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo sapiens] [gi: 31881630]
Compounds Active: 140;Â Tested: 1342
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Raymond Dingledine, Em...Â more

17: AID: 940Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [Primary Screening]
Source: Emory University Molecular Libraries Screening Center
Protein Target: prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo sapiens] [gi: 31881630]
Compounds Active: 2141;Â Tested: 255589
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Raymond Dingledine, Em...Â more

18: AID: 1420Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Dose Response Confirmation for Calpain Inhibitors [Confirmatory]
Source: Emory University Molecular Libraries Screening Center
Protein Target: calpain II [Sus scrofa] [gi: 1628587]
Compounds Active: 63;Â Tested: 1133
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Jonathan Glass, MD, Emory ...Â more

19: AID: 1419Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Literature, Other Links

Dose Response Confirmation for Small Molecule Inhibitors of Epstein-Barr Virus [Confirmatory]
Source: Emory University Molecular Libraries Screening Center
Protein Target: BZLF2 [Human herpesvirus 4 type 2] [gi: 139424501]
Compounds Active: 555;Â Tested: 849
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...Â more

20: AID: 1418Â Â Â Â Â Summary | Data (Active) Related BioAssays, Chemicals, Other Links

Dose Response Confirmation for Mcl-1/Bid Interaction Inhibitors [Confirmatory]
Source: Emory University Molecular Libraries Screening Center
Protein Target: Mcl-1 [Homo sapiens] [gi: 7582271]
Compounds Active: 509;Â Tested: 1176
Description: NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...Â more

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