Xylazine
From Wikipedia, the free encyclopedia
Xylazine
Systematic (IUPAC) name
2-(2,6-Dimethylphenylamino)-
5,6-dihydro-4H-thiazine
5,6-dihydro-4H-thiazine
Identifiers
ATC code ?
Chemical data
Mol. mass 220.33
Pharmacokinetic data
Therapeutic considerations
Legal status
Veterinary Use
Routes ?
Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other large mammals {non-human}. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. Yohimbine (Yobine) and atipamezole (commerical name Antisedan) can be used to reverse xylazine effects. In veterinary anesthesia, xylazine is often used in combination with ketamine. No formal information in humans available. Xylazine is sold by Bayer under the brand name Rompun.
This pharmacology-related article is a stub. You can help Wikipedia by expanding it.[edit] References
McCurnin, DM, and JM Bassert. Clinical Textbook for Veterinary Technicians, 5th ed. Saunders, Philadelphia, PA. 2002. Bayer Healthcare - Rompun Homepage http://www.rompun.com/. 2005. Wright, Dr. Bob. Human Health Concerns When Working With Medications Around Horses. Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA). http://www.omafra.gov.on.ca/english/livestock/horses/facts/00-063.html. 2005.
