Tacalcitol

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Tacalcitol

Systematic (IUPAC) name

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl

]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methyli denecyclohexane-1,3-diol

Identifiers

CAS number 57333-96-7

ATC code D05AX04

PubChem 5283734

Chemical data

Formula C₂₇H₄₄O₃ 

Mol. mass 416.64

Pharmacokinetic data

Bioavailability  ?

Metabolism  ?

Half life  ?

Excretion  ?

Therapeutic considerations

Pregnancy cat.

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Legal status

Routes Topical

Tacalcitol is a synthetic vitamin D₃ analogue that is used to treat psoriasis. Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes. Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

[edit] References

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