Medication

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Medication, also referred to as medicine, can be loosely defined as any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease.[1][2] Other synonyms include pharmacotherapy, pharmacotherapeutics, and drug treatment.

[edit] Classification

Medication can be usually classified in various ways, e.g. by its chemical properties, mode of administration, or biological system affected. An elaborate and widely used classification system is the Anatomical Therapeutic Chemical Classification System (ATC system).

Types of medicines:

Antipyretics  : reducing fever (pyrexia) Analgesics  : painkillers Anti-malarial drugs : treating malaria Antibiotics  : inhibiting germ growth Antiseptics  : prevention of germ growth near burns, cuts and wounds

[edit] Types of medications (type of pharmacotherapy)

[edit] For the gastrointestinal tract or digestive system

[edit] For the cardiovascular system

[edit] For the central nervous system

See also: Psychiatric medication

hypnotic, anaesthetics, antipsychotic, antidepressant (including tricyclic antidepressants, monoamine oxidase inhibitor, lithium salt, selective serotonin reuptake inhibitor), anti-emetic, anticonvulsant and antiepileptic, anxiolytic, barbiturate, movement disorder drug, stimulant (including amphetamines), benzodiazepine, cyclopyrrolone, dopamine antagonist, antihistamine, cholinergic, anticholinergic, emetic, cannabinoids, 5-HT antagonist

[edit] For pain & consciousness (analgesic drugs)

Further information: Analgesic

The main classes of painkillers are NSAIDs, opioids and various orphans such as paracetamol, tricyclic antidepressants and anticonvulsants.

[edit] For musculo-skeletal disorders

NSAIDs (including COX-2 selective inhibitors), muscle relaxant, neuromuscular drug
anticholinesterase

[edit] For the eye

General: adrenergic neurone blocker, astringent, ocular lubricant Diagnostic: topical anesthetics, sympathomimetics, parasympatholytics, mydriatics, cycloplegics Anti-bacterial: antibiotics, topical antibiotics, sulfa drugs, aminoglycosides, fluoroquinolones Anti-viral: Anti-fungal: imidazoles, polyenes Anti-inflammatory: NSAIDs, corticosteroids Anti-allergy: mast cell inhibitors Anti-glaucoma: adrenergic agonists, beta-blockers, carbonic anhydrase inhibitors/hyperosmotics, cholinergics, miotics, parasympathomimetics, prostaglandin agonists/prostaglandin inhibitors. nitroglycerin

[edit] For the ear, nose and oropharynx

sympathomimetic, antihistamine, anticholinergic, NSAIDs, steroid, antiseptic, local anesthetic, antifungal, cerumenolyti

[edit] For the respiratory system

bronchodilator, NSAIDs, anti-allergic, antitussive, mucolytic, decongestant
corticosteroid, beta-receptor antagonist, anticholinergic, steroid

[edit] For endocrine problems

androgen, antiandrogen, gonadotropin, corticosteroid, growth hormone, insulin, antidiabetic (sulfonylurea, biguanide/metformin, thiazolidinedione, insulin), thyroid hormones, antithyroid drugs, calcitonin, diphosponate, vasopressin analogues

[edit] For the reproductive system or urinary system

antifungal, alkalising agent, quinolones, antibiotic, cholinergic, anticholinergic, anticholinesterase, antispasmodic, 5-alpha reductase inhibitor, selective alpha-1 blocker, sildenafil, fertility medication

[edit] For contraception

[edit] For obstetrics and gynecology

NSAIDs, anticholinergic, haemostatic drug, antifibrinolytic, Hormone Replacement Therapy, bone regulator, beta-receptor agonist, follicle stimulating hormone, luteinising hormone, LHRH
gamolenic acid, gonadotropin release inhibitor, progestogen, dopamine agonist, oestrogen, prostaglandin, gonadorelin, clomiphene, tamoxifen, Diethylstilbestrol

[edit] For the skin

emollient, anti-pruritic, antifungal, disinfectant, scabicide, pediculicide, tar products, vitamin A derivatives, vitamin D analogue, keratolytic, abrasive, systemic antibiotic, topical antibiotic, hormones, desloughing agent, exudate absorbent, fibrinolytic, proteolytic, sunscreen, antiperspirant, corticosteroid

[edit] For infections and infestations

antibiotic, antifungal, antileprotic, antituberculous drug, antimalarial, anthelmintic, amoebicide, antiviral, antiprotozoal

[edit] For immunology

vaccine, immunoglobulin, immunosuppressant, interferon, monoclonal antibody

[edit] For allergic disorders

anti-allergic, antihistamine, NSAIDs

[edit] For nutrition

tonic, iron preparation, electrolyte, parenteral nutritional supplement, vitamins, anti-obesity drug, anabolic drug, haematopoietic drug, food product drug

[edit] For neoplastic disorders

cytotoxic drug, sex hormones, aromatase inhibitor, somatostatin inhibitor, recombinant interleukins, G-CSF, erythropoietin

[edit] For diagnostics

contrast media

[edit] For euthanasia

An euthanaticum is used for euthanasia and physician-assisted suicide, see also barbiturates.

Euthanasia is not permitted by law in many countries, and consequently medicines will not be licenesed for this use in those countries.

[edit] Legal considerations

Medications may be divided into over-the-counter drugs (OTC) which may be available without special restrictions, and prescription only medicine (POM), which must be prescribed by a licensed medical practitioner. The precise distinction between OTC and prescription depends on the legal jurisdiction.

The International Narcotics Control Board of the United Nations imposes a world law of prohibition of certain medications. They publish a lengthy list of chemicals and plants whose trade and consumption (where applicable) is forbidden. OTC medications are sold without restriction as they are considered safe enough that most people will not hurt themselves accidentally by taking it as instructed. Many countries, such as the United Kingdom have a third category of pharmacy medicines which can only be sold in registered pharmacies, by or under the supervision of a pharmacist.

[edit] Other/related topics

Polypharmacy: suggests that multiple use of prescribed and non-prescribed medications, (use of 5 or more), can have adverse effects on the recipient.

Zoopharmacognosy: Animal usage of drugs and non-foods.

[edit] Blockbuster drug

A blockbuster drug is a drug generating more than $1 billion of revenue for its owner each year. The search for blockbusters has been the foundation of the R&D strategy adopted by big pharmaceutical companies, but this looks set to change. New advances in genomics, and the promise of personalized medicine, are likely to fragment the pharmaceutical market.

A recent report from Urch Publishing estimated that about one third of the pharma market by value is accounted for by blockbusters. About 100 products are blockbusters. The top seller was Lipitor, a cholesterol-lowering medication marketed by Pfizer with sales of $12.2 billion.

[edit] Leading blockbuster drugs

Medication Trade name Company Sales[3][4] (billion $), year
atorvastatin Lipitor Pfizer 12 ('07) <
enoxaparin Lovenox or Clexane sanofi-aventis
celecoxib Celebrex Pfizer 2.3 2007
omeprazole Losec/Prilosec AstraZeneca 2.6 2004
esomeprazole Nexium AstraZeneca 3.3 2003
Fexofenadine Telfast/Allegra Aventis 1.87 2004
quetiapine Seroquel AstraZeneca 1.5 2003
metoprolol Seloken/Toprol AstraZeneca 1.3 2003
budesonide Pulmicort/Rhinocort AstraZeneca 1.3 2003 (plus some fraction of the $0.6bn sales of Symbicort)

[edit] See also

[edit] References

[edit] External links


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