Aprobarbital
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Aprobarbital
Systematic (IUPAC) name
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Identifiers
Chemical data
Mol. mass 210.23 g/mol
Synonyms Aprobarbital, Oramon, Allylpropymal, Alurate, 5-Isopropyl-5-allylbarbituric acid
Pharmacokinetic data
Therapeutic considerations
Routes ?
Aprobarbital (Oramon) is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. [1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
[edit] References
^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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