Alpha-2 blocker
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Although alpha blocker generally refers to α1-blockers, there are also α2-blockers, which are antagonists to the α2 adrenergic receptor. They are mainly used in research, finding little clinical application.
[edit] Examples
Examples include atipamezole,[1]efaroxan, idazoxan,[2]yohimbine, benzylpiperazine, and rauwolscine.
[edit] References
^ Haapalinna A, Leino T, Heinonen E (November 2003). "The alpha 2-adrenoceptor antagonist atipamezole potentiates anti-Parkinsonian effects and can reduce the adverse cardiovascular effects of dopaminergic drugs in rats". Naunyn Schmiedebergs Arch. Pharmacol. 368 (5): 342–51. doi:. PMID 14566451. ^ Chopin P, Colpaert FC, Marien M (February 1999). "Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway". J. Pharmacol. Exp. Ther. 288 (2): 798–804. PMID 9918591.
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